Dodecalypse is mentioned in The Prophecy: "As the Sacred Lord purged the mighty inferno of Dodecalypse, his body began to disintegrate. The Evil has been vanquished. Thus, my life's purpose is complete. And in this great deed that brought life and happiness to the Furons, The Lord of the Sacred Crotch sunk low through space to the oasis of Earth, to sink into the fertile soul of its land..."
- ""That bastard's been screwing with me since day one."
- ―-Arkvoodle complaining about Dodecalpse[src]
In Destroy All Humans! 2, Arkvoodle speaks of the evil of Dodecalypse.
Seemingly, Arkvoodle personifies what Furons consider good, while Dodecalypse personifies what Furons consider evil in a Dualistic pantheon, meaning they are essentially deities who are of roughly equal power, and evenly matched. Popular opinion has it that Arkvoodle is meant as an allegory to the Christian deity, and Dodecalypse is meant as an allegory to Lucifer, the chief fallen angel (otherwise known as The Devil) from Christianity.