The Furon Mothership was a space station in orbit of the planet Earth.
The Mothership was positioned above earth, orbiting much like a satellite. Between missions, Crypto would return to The Mothership to obtain updates and the like. It's appearance was akin to a mushroom with a fatter base, floating above earth with a purple beam of light coming from the bottom to guide Crypto around the surface of Earth. It housed Gastro, Crypto, and Orthopox, along with living quarters and Pox's laboratory where he directed Crypto from mission to mission and sold him upgrades in exchange for DNA. It didn't seem to move around much except from Furon to Earth; however it did rotate while in orbit.
The Furon Mothership's main sight was the puple light that it would emit from its base. The station had extensive arrays of sensor devices, provided by the Furon Empire, for tracking humans and mapping areas on a planet.
After the death of Cryptosporidium 136, Orthopox 13 defended the idea of going to Earth to collect the pure Furon DNA from human brain stems, in front of the Furon council. After the events of Destroy All Humans!, Pox began experimenting on live human brains, eyes and all. After his victory over the American government, Crypto began spending less time on the Mothership and more time on Earth and in the White House.10 years after arriving on Earth, the mothership was destroyed by a KGB ICBM missile. The debris from the mothership's destruction burned up in the Earth's atmosphere, while items such as datacores and furotech cells were able to survive.